English
Bulgarian Structure (48)
Department of Epidemiology (7)
DEPARTMENT EPIDEMIOLOGY AND DDD
The main aspects of the department’s activity:
- scientific and research activities aiming to achieve effective national communicable disease (CD) surveillance and control, incl. immunoprophylaxis and implementation of disinfection, sterilization and vector control practices;
- participation in the preparation ofdisease prevention programs, regulations and guidance documents of Ministry of Health (MoH)
- provision of expert advice and conduction of postgraduate courses for medical specialists from Regional Health Inspectorates (RHIs);
- media dissemination of health knowledge to public.
Laboratory “Chemistry of DDD”
LABORATORY "CHEMISTRY OF DDD"
Contact:
Sofia 1233, Blvd. "General Stoletov" 44A,
tel. 02/831 00 30
Work time:
from 7.30 a.m. to 2.30 p.m
Head of Laboratory:
Irena Christoskova - Dacheva
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Laboratory staff:
Eng. Rositsa Madzharova, chemist
Lubomira Bozhilova, biologist
Eli Dimitrova, laboratory assistant
Elka Yancheva, laboratory worker
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
The activity of the laboratory is related to:
- Development of analytical methods for qualitative and quantitative control of biocides;
- Determination of the physico-chemical characteristics of disinfectants;
- Quantification of the included active substances (AB) in disinfectants and prepared working solutions;
- Tracking the stability of AB over time;
- Disinfection control through express and quantitative chemical methods;
- Compilation of disinfection regimes;
- Carrying out quantitative tests of disinfectants, according to the requirements of the BDS/EN/ISO17025 standard;
- Production of chemical indicators for daily control of sterilization at 121°C, 134°C and 165°C with a certified quality management system BDS/EN/ISO9001;
- Consultations for interested persons on disinfection and sterilization;
- Conducting thematic courses for postgraduate studies and individual training of disinfection and sterilization specialists.
PRICE LIST
of the paid services provided by NCIPD, MS№ 255/17.10.2012, 81/ 23.10.2012
|
Code |
TESTING |
Price /in BGN/ |
|
611 |
Quantitative determination in %: Active chlorine Iodine Formaldehyde Phenolic derivatives |
42,00 |
|
613 |
Quantitative determination of chlorhexidine digluconate in % |
47,00 |
|
614 |
Quantitative determination of quaternary ammonium salts in % |
56,00 |
|
618 |
Quantitative determination in %: Glutaraldehyde Glyoxal Total Aldehydes |
60,00 |
|
624 |
Quantitative determination of active oxygen/perhydrol in % |
32,00 |
|
611 + 624 |
Quantitative determination of peracetic acid in % |
74,00 |
Laboratory “Medical arachnoenthomology and zoology with disinsection and deratization”
LABORATORY “MEDICAL ARACHNOENTHOMOLOGY AND ZOOLOGY WITH DISINSECTION AND DERATIZATION”
Head of laboratoty: Nadya Mitkova
Contacts: tel +3592 94 46 999/324
This email address is being protected from spambots. You need JavaScript enabled to view it.
Staff:
Sofia Boneva, biologist
Tamara Lazarova, biologist
Emilia Vesheva, laboratory worker
e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Main activities:
- To study the spread, seasonal activity, biology and ecology of arthropods and rodents – vectors and reservoirs of CDs
- To study the epidemiological role of arthropods and rodents as vectors and reservoirs of CDs
- To study the biological effectiveness of biocides
- Testing the susceptibility of arthropods to different insecticides
- To publish studies results in specialized journals
- To assist MoH in development of ordinances and guidance materials
- To participate in MoH commissions of experts
- To teach DDD specialists
Activity on scientific projects:
1. Role of migratory and native wild birds as reservoirs of vector-transmitted infections in humans. Funded by Bulgarian Fund for scientific investigation /№ КП-06-Н33/16 from 21.12.2019
2. The role of cave-dwelling bat species in Bulgaria as vectors and reservoirs of European bat lyssaviruses. Funded by Bulgarian Fund for scientific investigations /№ КП-06-Н31/14 from 11.12.2019
3. Biological and molecular genetic studies on the insecticide resistance of native and invasive mosquito species. Funded by Bulgarian Fund for scientific investigations/ № КП-06-Н41/5 from 30.11.2020.
Written by AdministratorLaboratory “Disinfection, Sterilization and Biological indicators
Laboratory “Disinfection, Sterilization and Biological indicators”
Tel: +3592 832 81 92
e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; This email address is being protected from spambots. You need JavaScript enabled to view it.
Staff:
Head of laboratory: Milena Nikolova, Chief assistant, PhD
Svetlana Yordanova, biologist
Gergana Getova, biologist
Bistra Alexandrova, lab. worker
Main activities:
- To study methods and agents for disinfection and sterilization
- To prepare disinfection schemes for sites with epidemiological significance
- To assist MoH in development of ordinances, guidance materials, and medical standards concerning HAI, disinfection, sterilization and pest-control activity
- To participate in MoH commissions of experts and working groups
- To evaluate antimicrobial effectiveness of disinfectants and medical devices under laboratory and practical conditions
- To conducts annually training for students, biologists, medical doctors and laboratory specialists as part of their postgraduate courses and as part of the educational courses for medical specialties in Microbiology, Virology and Epidemiology and other specialties. The specialists conduct trainings for graduates and doctoral students.
- To assist to Regional Health Inspectorates (RHIs) and all other healthcare facilities, citizens and pest-control operators in the country;
Disinfectants and antiseptics are tested in the laboratory according to the following standard methods:
EN 1040 Chemical disinfectants and antiseptics - Quantitative suspension test for the evaluation of basic bactericidal activity of chemical disinfectants and antiseptics - Test method and requirements (phase 1);
EN 1275 Chemical disinfectants and antiseptics - Quantitative suspension test for the evaluation of basic fungicidal or basic yeasticidal activity of chemical disinfectants and antiseptics - Test method and requirements (phase 1);
EN 14561 Chemical disinfectants and antiseptics - Quantitative carrier test for the evaluation of bactericidal activity for instruments used in the medical area - Test method and requirements (phase 2, step 2);
EN 14562 Chemical disinfectants and antiseptics - Quantitative carrier test for the evaluation of fungicidal or yeasticidal activity for instruments used in the medical area - Test method and requirements (phase 2, step 2);
EN 1276 Chemical disinfectants and antiseptics. Quantitative suspension test for the evaluation of bactericidal activity of chemical disinfectants and antiseptics used in food, industrial, domestic and institutional areas. Test method and requirements (phase 2, step 1);
EN 1650 Chemical disinfectants and antiseptics - Quantitative suspension test for the evaluation of fungicidal or yeasticidal activity of chemical disinfectants and antiseptics used in food, industrial, domestic and institutional areas - Test method and requirements (phase 2, step 1);
EN 13727 Chemical disinfectants and antiseptics. Quantitative suspension test for the evaluation of bactericidal activity in the medical area. Test method and requirements (phase 2, step 1);
EN 13624 Chemical disinfectants and antiseptics - Quantitative suspension test for the evaluation of fungicidal or yeasticidal activity in the medical area - Test method and requirements (phase 2, step 1);
EN 13697 Chemical disinfectants and antiseptics - Quantitative non-porous surface test for the evaluation of bactericidal and yeasticidal and/or fungicidal activity of chemical disinfectants used in food, industrial, domestic and institutional areas without mechanical action - Test method and requirements without mechanical action (phase 2, step 2);
EN 1500 Chemical disinfectants and antiseptics - Hygienic handrub - Test method and requirements (pase 2/step 2);
EN 1499 Chemical disinfectants and antiseptics - Hygienic handwash - Test method and requirements (phase 2/step 2);
EN 12791 Chemical disinfectants and antiseptics - Surgical hand disinfection - Test method and requirements (phase 2, step 2).
Methods EN 1040; EN 1275 and EN 13697 are included in the scope of accreditation in accordance with the requirements of EN ISO 17025.
Written by AdministratorINTRODUCTION TO FLOW CYTOMETRY
Theoretical course for beginners
Sofia, NCIPD, 13 - 15.04.2010
PROGRAM
30.03 (02.04)
- 09.00 – 10.00
- Opening. History and principles of flow cytometry, (Prof. Taskov).
- 10.15 – 11.30
- Basic flow cytometer configuration (fluidic system, optical system, electronics). Last generation systems for flow cytometry analysis and cell sorting, (Prof. Taskov).
- 11.45 – 12.30
- Fluorescence and fluorochromes in flow cytometry. Principles of multi-color analysis. (A. Mihova)
- 13.30 – 14.30
- Possibilities of flow cytometry analysis (cells – subcellular fractions – soluble analytes), (Prof. Taskov, assoc.prof. M. Nikolova).
31.03 (03.04)
- 09.00 – 09.30
- Monoclonal antibodies. Immunophenotyping. Analysis of surface and intracellular markers, (Assoc.prof. M. Nikolova).
- 10.45 – 12.00
- Flow cytometry analysis of cellular functions – I (activation, proliferation, cytokine expression), (Assoc.prof. M. Nikolova, M. Muhtarova).
- 13.00 – 14.30
- Flow cytometry analysis of cellular functions – II (migration, phagocytosis, oxidative burst, allergen-specific degranulation) (Assoc.prof. M. Nikolova, D.Stankulova).
- 15.00 – 16.30
- Apoptosis, (A. Mihova, M.Muhtarova).
01.04 (04.04)
- 09.00 – 10.00
- Analysis of DNA and cell cycle, (A. Mihova).
- 10.15 – 11.15
- Clinical applications of flow cytometry (Assoc. prof. M.Nikolova)
- 11.30 - 12.30
- Design of flow cytometry experiments: planning, performing, data analysis and publication, (Prof. Taskov).
- 13.30 – 14.30
- Discussion and closure, (Prof. Taskov).
Registration:
Registration fee: 45 lv. The number of participants is limited!
For additional information and registration:
- Dr. Maria Nikolova, Antoaneta Mihova
- tel.
- 359 2 943 56 36
- This email address is being protected from spambots. You need JavaScript enabled to view it.
COMING SOON:
Practical Course: Flow Cytometry DNA Analysis, May and October 2010
Practical Course: Flow Cytometry Analysis of Apoptosis, June 2010
Written by Super User
Cell cultures
Head: Assoc. Prof. D-r Daniela Dundarova, M.D.
Producing, maintaining and supplying all laboratories in the country with adequate quantities of quality call cultures and food media. Cell bank with over 70 well preserved cell lines and diploid cell cultures.
New technologies for producing of diploid cell cultures from different human and animal tissues.Methods for analysis and cryogenic conservation of cultivating cells.
Written by Super UserRetroviruses
Molecular Virology
Head Assoc. Prof. Zlatko Kalvachev, M.D. PhD
Molecular-virological diagnostics of papillomavirus infections. High quality diagnostic with standard and multiple PCR test of human papillomaviruses genotype.
Written by Super UserArboviruses
Head Assoc. Prof. Gavril Katzarov, M.D.
Laboratory testing of suspected cases for Congo-Crimean Hemorrhagic fever, Hemorrhagic nephrosonephritis and Meningitis lymphocitaria.
Written by Super User
NRCL of HIV / AIDS
NATIONAL CENTER OF INFECTIOUS AND PARASITIC DISEASES (NCIPD)
DEPARTMENT OF VIROLOGY
NATIONAL REFERENCE CONFIRMATORY LABORATORY OF HIV
Address: N. Stoletov Blvd. 44A, Sofia 1233; Phone 02 9318071; e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Laboratory staff:
- Head of the Laboratory: Associate Professor Ivailo Alexiev PhD
- Chief Assistant Reneta Dimitrova PhD
- Anna Hristova – biologist
- Asya Kostadinova – biologist
- Alexandra Partsuneva - biologist
- Lyubomira Grigorova – biologist
- Rashka Hristova - laboratory worker
NRCL of HIV at the NCIPD provides confirmatory diagnostics and virological monitoring of patients with HIV/AIDS in Bulgaria.
Diagnostics of HIV
NRCL of HIV is the only reference laboratory in the country that provides the final confirmatory diagnostics of HIV and registers the individuals infected with HIV. The laboratory performs diagnostic, confirmatory, specialized and unique tests using a wide range of methods, including: 4th generation ELISA Ag/Ab, confirmatory Western blot (LIA) test, Real-time PCR, sequencing of the viral genome and rapid tests for HIV. Serological and molecular-biological analyses are carried out for diagnostics and also virological control of HIV infection in pregnant women and newborn children. NRCL of HIV conducts analysis for the detection of early HIV infection in order to monitor the development of the epidemic in the country.
Virological monitoring of HIV infection
NRCL of HIV also provides viral load tests using Real-time PCR and antiretroviral drug resistance tests by sequencing and genotyping of the viral genome to monitor the success of antiretroviral therapy and patients' follow-up.
Participation in inter-laboratory and international control
NRCL of HIV annually conducts a national inter-laboratory control of laboratories that perform HIV testing. The NRCL of HIV participates in this control as well as in international inter-laboratory control conducted by INSTAND, Germany. The purpose of these controls is to ensure that serological markers for HIV infection tested with ELISA Ag/Ab, confirmatory test WB, and molecular biological methods, including viral load by Real-time PCR and tests for resistance to antiretroviral drugs, by sequencing and genotyping of the viral genome, meet the required standards for quality assurance and standardization in laboratory medicine.
Education and courses
The NRCL of HIV conducts annual training for students, biologists, medical doctors, and laboratory specialists as part of their postgraduate courses and educational courses for medical specialties in Microbiology, Virology, Epidemiology, and other relevant fields. Additionally, the NRCL of HIV provides training for graduates and PhD students.
Organizational and methodical activities
The NRCL of HIV participates in expert groups dedicated to the development of national guidelines for diagnostics and therapy of persons with HIV/AIDS in Bulgaria. The NRCL of HIV also takes part in anti-AIDS campaigns to promote the prevention of HIV/AIDS and other sexually and blood-borne infectious diseases. Moreover, the NRCL of HIV conducts training sessions for associates from NGOs and Regional Health Inspectorates to provide voluntary counseling and testing for HIV in low-threshold centers for health and social services for individuals who belong to groups at the highest risk.
Scientific activities
The NRCL of HIV actively participates in national and international scientific studies and projects to monitor HIV drug resistance, as well as the introduction and spread of different HIV genotypes in Bulgaria and Europe. The laboratory also attends national and international scientific congresses and collaborates with other laboratories and research institutes in Bulgaria and other countries. Furthermore, the NRCL of HIV is responsible for organizing the annual National Scientific Conference on HIV and co-infections.
Selected publications:
Marta Giovanetti, Eleonora Cella, Ivan N. Ivanov, Lyubomira Grigorova, Ivan Stoikov, Deyan Donchev, Reneta Dimitrova, Svetoslav Nanev Slavov, Carla Nartuhi Mavian, Vagner Fonseca, Fabio Scarpa, Alessandra Borsetti, Neli Korsun, Ivelina Trifonova, Veselin Dobrinov, Todor Kantardjiev, Iva Christova, Massimo Ciccozzi, Ivailo Alexiev
Genomic Epidemiology and Lineage Dynamics of SARS-CoV-2 in Bulgaria: Insights from a Three-Year Pandemic Analysis. Viruses 2023, 15, 1924.
https://doi.org/10.3390/v15091924
Impact Factor: 4.7
Alexiev, I., Ivanov, I., Giovanetti, M., Cella, E., Stoikov, I., Donchev, D., Grigorova L., Gancheva A., Dimitrova R., Scarpa F., Korsun N., Trifonova I., Dobrinov V., Kantardjiev T., Christova I., & Ciccozzi, M. (2023). Early Detection of the Recombinant SARS-CoV-2 XAN Variant in Bulgaria: Initial Genomic Insights into Yet Another Piece of the Growing Puzzle of Recombinant Clades. Microorganisms, 11(8), 2041.
https://www.mdpi.com/2076-2607/11/8/2041
Impact Factor: 4.5
Alexiev, I., Shankar, A., Pan, Y., Grigorova, L., Partsuneva, A., Dimitrova, R., Gancheva A., Kostadinova A., Elenkov I., Yancheva N., Grozdeva R., Strashimirov D., Stoycheva M., Baltadzhiev I., Doichinova T., Pekova L., Kosmidis M., Emilova R., Nikolova M. and Switzer, W. M. (2023). Transmitted HIV Drug Resistance in Bulgaria Occurs in Clusters of Individuals from Different Transmission Groups and Various Subtypes (2012–2020). Viruses, 15(4), 941. https://doi.org/10.3390/v15040941
Impact Factor: 4.7
Alexiev, I.; Shankar, A.; Pan, Y.; Grigorova, L.; Partsuneva, A.; Dimitrova, R.; Gancheva, A.; Kostadinova, A.; Elenkov, I.; Yancheva, N.; Grozdeva, R.; Strashimirov, D.; Stoycheva, M.; Baltadzhiev, I.; Doichinova, T.; Pekova, L.; Kosmidis, M.; Emilova, R.; Nikolova, M.; Switzer, W.M.
Transmitted HIV Drug Resistance in Bulgaria Occurs in Clusters of Individuals from Different Transmission Groups and Various Subtypes (2012–2020). Viruses 2023, 15, 941. https://doi.org/10.3390/v15040941
Impact factor: 4.7
Alexiev, I., Giovanetti, M., Cella, E., Ivanov, I., Stoikov, I., Donchev, Lubomira Grigorova, Anna Gancheva, Reneta Dimitrova, Nelly Korsun, Ivelina Trifonova, Ivva Philipova, Veselin Dobrinov, Iliana Grigorova, Todor Kantardjiev, Iva Christova, Massimo Ciccozzi.
Initial Introduction and Spread of the SARS‐CoV‐2 AY. 4.2.1 Delta Variant in Bulgaria, a Genomic Insight.
Journal of Medical Virology.
PMID: 35902787 DOI: 10.1002/jmv.28033
https://onlinelibrary.wiley.com/doi/10.1002/jmv.28033
Impact Factor: 20.693
Luka Jovanovic, Marina Siljic, Valentina Cirkovic, Dubravka Salemovic, Djordje Jevtovic, Ivailo Alexiev, Snjezana Zidovec-Lepej, Maja Oroz, Josip Begovac, Dimitrios Paraskevis, Lemonia Skoura, Dimitrios Chaztidimitriou, Evangelia G Kostaki, Snezana Dragas, Brankica Dupanovic, Dan Otelea, Simona Paraschiv, Mario Poljak, Maja M Lunar, Maja Stanojevic
(2022). HIV-1 subtype B spread through cross-border clusters in the Balkans: a molecular analysis in view of incidence trends. AIDS (London, England).
https://journals.lww.com/aidsonline/Abstract/9900/HIV_1_subtype_B_spread_through_cross_border.115.aspx
DOI: 10.1097/QAD.0000000000003394
Impact Factor: 4.177
Ivailo Alexiev, Carla Mavian, Taylor Paisie, Massimo Ciccozzi, Reneta Dimitrova, Anna Gancheva, Asya Kostadinova, Carole Seguin-Devaux and Marco Salemi.
Analysis of the Origin and Dissemination of HIV-1 Subtype C in Bulgaria
Viruses 2022, 14(2), 263; https://doi.org/10.3390/v14020263
https://www.mdpi.com/1999-4915/14/2/263
Impact Factor: 5.048
Ivailo Alexiev*, Ivan Ivanov*, Ivva Philipova, Nelly Korsun, Ivan Stoykov, Reneta Dimitrova, Lubomira Grigorova, Anna Gancheva, Ivelina Trifonova, Veselin Dobrinov, Iliana Grigorova, Alexey Savov, Boryana Asenova, Massimo Ciccozzi, Todor Kantardjiev.
Postvaccination SARS-CoV-2 Alpha (B.1.1.7) Lineage Infection among Healthcare Workers on the Background of IgG Antibodies
Journal of Medical Virology. First published: 2021-10-14 | journal-article. DOI: 10.1002/jmv.27394
https://onlinelibrary.wiley.com/doi/10.1002/jmv.27394
Impact Factor: 20.693
Alexiev I, Campbell EM, Knyazev S, Pan Y, Grigorova L, Dimitrova R, Partsuneva A, Gancheva A, Kostadinova A, Seguin-Devaux C, Elenkov I, Yancheva N, Switzer WM.
Molecular Epidemiological Analysis of the Origin and Transmission Dynamics of the HIV-1 CRF01_AE Sub-Epidemic in Bulgaria. Viruses. 2021; 13(1):116.
https://www.mdpi.com/1999-4915/13/1/116#cite
Impact Factor: 3.811
T Balayan J Begovac A Skrzat‐Klapaczyńska I Aho I Alexiev P Bukovinova D Salemovic D Gokengin A Harxhi T Holban D Jevtovic K Kase B Lakatos I Latysheva R Matulionyte C Oprea A Papadopoulos N Rukhadze D Sedlacek J Tomazic A Vassilenko M Vasylyev A Verhaz N Yancheva O Yurin A Horban JD Kowalska on behalf of the ECEE Network Group.
Where are we with pre‐exposure prophylaxis use in Central and Eastern Europe? Data from the Euroguidelines in Central and Eastern Europe (ECEE) Network Group. HIV medicine, 2020.First published: 05 October 2020
https://onlinelibrary.wiley.com/doi/epdf/10.1111/hiv.12960
Impact Factor: 3.734
Alexiev, I.; M. Campbell, E.; Knyazev, S.; Pan, Y.; Grigorova, L.; Dimitrova, R.; Partsuneva, A.; Gancheva, A.; Kostadinova, A.; Seguin-Devaux, C.; M. Switzer, W.
Molecular Epidemiology of the HIV-1 Subtype B Sub-Epidemic in Bulgaria. Viruses 2020, 12, 441.
https://www.mdpi.com/1999-4915/12/4/441
Impact Factor: 3.811
Ivailo Alexiev, Elitsa Golkocheva-Markova, Asya Kostadinova, Reneta Dimitrova, Lora Nikolova, Anna Gancheva, Tencho Tenev, Ivaylo Elenkov, Tatiana Tcherveniakova, Nina Yancheva, Mariyana Stoycheva, Tsetsa Doychinova, Lilia Pekova, Marina Alexandrova, Andon Timchev, Dimitar Strashimirov & Maria Nikolova (2019).
The prevalence of hepatitis B and C co-infections among people with HIV-1 in Bulgaria: 2010–2015. Future Virology, 14(12), 791-798.
https://www.futuremedicine.com/doi/abs/10.2217/fvl-2019-0092
Impact Factor: 0.730
Ganova-Raeva L, Dimitrova Z, Alexiev I, Punkova L, Sue A, Guo-liang Xia, Anna Gancheva, Reneta Dimitrova, Asya Kostadinova, Elitsa Golkocheva-Markova, Yury Khudyakov (2019)
HCV transmission in high-risk communities in Bulgaria.
PloS one, 2019, 14.3: e0212350. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212350
Impact Factor: 2.766
Lore Vinken, Katrien Fransen, Lize Cuypers, Ivailo Alexiev, Claudia Balotta, Laurent Debaisieux, Carole Seguin-Devaux, Sergio García Ribas, Perpétua Gomes, Francesca Incardona, Rolf Kaiser, Jean Ruelle, Murat Sayan, Simona Paraschiv, Roger Paredes, Martine Peeters, Anders Sönnerborg, Ellen Vancutsem, Anne-Mieke Vandamme, Sigi Van den Wijngaert, Marc Van Ranst, Chris Verhofstede, Tanja Stadler, Philippe Lemey and Kristel Van Laethem (2019). Earlier initiation of antiretroviral treatment coincides with an initial control of the HIV-1 sub-subtype F1 outbreak among men-having-sex-with-men in Flanders, Belgium.
Frontiers in Microbiology, 2019, 10, 613.
https://www.frontiersin.org/articles/10.3389/fmicb.2019.00613/full
Impact Factor: 4.019
Vic Arendt, Laurence Guillorit, Alain Origer, Nicolas Sauvageot, Michel Vaillant, Aurélie Fischer, Henri Goedertz, Jean-Hugues François, Ivailo Alexiev, Thérèse Staub, Carole Seguin-Devaux (2019). Injection of cocaine is associated with a recent HIV outbreak in People Who Inject Drugs in Luxembourg.
PloS one, 14(5), e0215570.
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215570
Impact Factor: 2.766
N.S. Sherriff, A.M. Jones, M. Mirandola, L. Gios, U. Marcus, C. Llewellyn, M. Rosinska, C. Folch, S. Dias, I. Toskin, I. Alexiev, S. Kühlmann-Berenzon, Sialon II Network
Factors related to condomless anal intercourse between men who have sex with men: results from a European bio-behavioural survey.
Journal of Public Health, fdz052, https://doi.org/10.1093/pubmed/fdz052
Published: 15 May 2019
Impact Factor: 1.670
Massimo Mirandola, Lorenzo Gios, Nigel Sherriff, Ulrich Marcus, Igor Toskin, Magdalena Rosinska, Susanne Schink, Sharon Kühlmann-Berenzon, Barbara Suligoi, Cinta Folch, Christiane Nöstlinger, Sonia Dias, Danica Stanekova, Irena Klavs, Saulius Caplinskas, Alexandru Rafila, Carolina Marin, Ivailo Alexiev, Lev Zohrabyan, Teymur Noori, Cinthia Menel-Lemos
Quantifying unmet prevention needs among MSM in Europe through a multi-site bio-behavioural survey.
Eurosurveillance, 2018, 23.49.
https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2018.23.49.1800097
Impact Factor: 7.1
Ulrich Marcus,; Susanne Barbara Schink; Nigel S. Sherrif; Anna-Marie Jones; Lorenzo Gios; Cinta Folch; Torsten Berglund; Christiana Nöstlinger; Marta Niedzwiedzka-Stadnik; Sonia F. Dias; Ana F. Gama; Emilia Naseva; Ivailo Alexiev; Danica Stanekova; Igor Toskin; Daniela Pitigoi; Alexandru Rafila; Irena Klavs; Massimo Mirandola
HIV serostatus knowledge and serostatus disclosure with the most recent anal intercourse partner in a European MSM sample recruited in 13 cities: Results from the Sialon-II study
BMC Infectious Diseases, Published: 25 November 2017
https://doi.org/10.1186/s12879-017-2814-x
Impact Factor: 2.768
Ivailo Alexiev, Alessandra Lo Presti, Reneta Dimitrova, Brian Thomas Foley, Anna Gancheva, Asya Kostadinova, Lora Nikolova, Silvia Angeletti, Eleonora Cella, Ivaylo Elenkov, Mariana Stoycheva, Daniela Nikolova, Tsetsa Doychinova, Liliya Pekova, Massimo Ciccozzi.
Origin and Spread of HIV-1 Subtype B among Heterosexual Individuals in Bulgaria
AIDS Res Hum Retroviruses. 2017 Dec 19
DOI: 10.1089/AID.2017.0167
http://online.liebertpub.com/doi/abs/10.1089/AID.2017.0167
Impact Factor: 2.095
Alexiev I, Alexandrova M, Golkocheva-Markova E, Teoharov P, Gancheva A, Kostadinova A, Dimitrova R, Elenkov I, Chervenjakova T, Stoycheva M, Nikolova D, Varleva T, Nikolova M.
High Rate of Hepatitis B and C Co-infections among People Living with HIV-1 in Bulgaria: 2010-2014.
AIDS Res Hum Retroviruses. 2016 Nov 14. [Epub ahead of print], doi:10.1089/AID.2016.0148.
PMID: 27841662
Impact Factor: 2.325
Gkikas Magiorkinis, Konstantinos Angelis, Ioannis Mamais, Aris Katzourakis, Angelos Hatzakis, Jan Albert, Glenn Lawyer, Osamah Hamouda, Daniel Struck, Jurgen Vercauteren, Annemarie Wensing, Ivailo Alexiev, Birgitta Åsjö, Claudia Balotta, Ricardo J. Camacho, Suzie Coughlan, Algirdas Griskevicius, Zehava Grossman, Anders Horban, Leondios G. Kostrikis, Snjezana J. Lepej, Kirsi Liitsola, Marek Linka, Claus Nielsen, Dan Otelea, Roger Paredes, Mario Poljak, Elizabeth Puchhammer-Stöckl, Jean Claude Schmit, Anders Sönnerborg, Danica Staneková, Maja Stanojevic, Charles A.B. Boucher, Georgios Nikolopoulos, Tetyana Vasylyeva, Samuel R. Friedman, D.A.M.C. van de Vijver, G. Angarano, M-L. Chaix, A. de Luca, K. Korn, C. Loveday, V. Soriano, S. Yerly, M. Zazzi, Anne-Mieke Vandamme, Dimitrios Paraskevis.
The global spread of HIV-1 subtype B epidemic
Infection, Genetics and Evolution (2016). doi:10.1016/j.meegid.2016.05.041
Impact Factor: 3.015
M. Alexandrova, E. Golkocheva-Markova, А. Timchev, N. Yancheva, I. Elenkov, I. Alexiev, P. Teoharov, T. Varleva, M. Nikolova
HCV co-infection compromising the effects of c-ART – an insight from the HIV-positive population in Bulgaria
International Journal of Science and Research (IJSR), Sep 2016 , ISSN (Online): 2319-7064
Impact Factor: 0.23
Ivailo Alexiev,Anupama Shankar, Reneta Dimitrova, Anna Gancheva, Asia Kostadinova, Pavel Teoharov, Elitsa Golkocheva, Maria Nikolova, Mariya Muhtarova, Ivaylo Elenkov, Mariyana Stoycheva, Daniela Nikolova, Tonka Varleva, and William M. Switzer.
Origin and spread of HIV-1 in persons who inject drugs in Bulgaria.
Infection, Genetics and Evolution (2016). doi:10.1016/j.meegid.2016.05.029
Impact Factor: 3.015
Lorenzo Gios, Massimo Mirandola, Igor Toskin, Ulrich Marcus, Sandra Dudareva-Vizule, Nigel Sherriff, Michele Breveglieri, Martina Furegato, Cinta Folch, Laia Ferrer, Alexandra Montoliu, Christiana Nöstlinger, Wim Vanden Berghe, Sharon Kühlmann-Berenzon, Inga Velicko, Sónia Dias, Barbara Suligoi, Vincenza Regine, Danica Stanekova, Magdalena Rosińska, Saulius Caplinskas, Irena Klavs, Ivailo Alexiev and Alexandru Rafila.
Bio-behavioural HIV and STI surveillance among men who have sex with men in Europe: the Sialon II protocols
BMC Public HealthBMC series – open, inclusive and trusted 2016 16:212DOI: 10.1186/s12889-016-2783-9
Impact Factor: 2.264
L. Marije Hofstra, Nicolas Sauvageot, Jan Albert, Ivailo Alexiev, Federico Garcia, Daniel Struck, David A.M.C. Van de Vijver, Birgitta Åsjö, Danail Beshkov, Suzie Coughlan, Diane Descamps, Algirdas Griskevicius, Osamah Hamouda, Andrzej Horban, Marjo Van Kasteren, Tatjana Kolupajeva, Leondios G. Kostrikis, Kirsi Liitsola, Marek Linka, Orna Mor, Claus Nielsen, Dan Otelea, Dimitrios Paraskevis, Roger Paredes, Mario Poljak, Elisabeth Puchhammer-Stöckl, Anders Sönnerborg, Danica Staneková, Maja Stanojevic, Kristel Van Laethem, Maurizio Zazzi, Snjezana Zidovec Lepej, Charles A.B. Boucher, Jean-Claude Schmit and Annemarie M.J. Wensing on behalf of the SPREAD program.
Transmission of HIV drug resistance and the predicted effect on current first-line regimens in Europe
Clin Infect Dis. (2015) doi:10.1093/cid/civ963 First published online:November 29, 2015
Impact Factor: 8.886
M. Casadellà, P. M. van Ham, M. Noguera-Julian, A. van Kessel, C. Pou, L. M. Hofstra, J. R. Santos, F. Garcia, D. Struck, I. Alexiev, A. M. Bakken Kran, A. I. Hoepelman, L. G. Kostrikis, S. Somogyi, K. Liitsola, M. Linka, C. Nielsen, D. Otelea, D. Paraskevis, M. Poljak, E. Puchhammer-Stöckl, D. Staneková, M. Stanojevic, K. Van Laethem, S. Zidovec Lepej, B. Clotet, C. A. B. Boucher, R. Paredes, and A. M. J. Wensing on behalf of the SPREAD programme.
Primary resistance to integrase strand-transfer inhibitors in Europe
J. Antimicrob. Chemother. first published online July 17, 2015doi:10.1093/jac/dkv202
Impact Factor: 5.439
Ivailo Alexiev, Anupama Shankar, A.M.J. Wensing, Danail Beshkov, Ivaylo Elenkov, Mariyana Stoycheva, Daniela Nikolova, Maria Nikolova, William M. Switzer.
Low HIV-1 Transmitted Drug Resistance in Bulgaria against a Background of High Clade Diversity
Journal of Antimicrob Chemother 2015; doi:10.1093/jac/dkv011
Impact Factor: 5.439
Konstantinos Angelis; Jan Albert; Ioannis Mamais; Gkikas Magiorkinis; Angelos Hatzakis; Osamah Hamouda; Daniel Struck; Jurgen Vercauteren; Annemarie M.J. Wensing; Ivailo Alexiev; Birgitta Asjo; Claudia Balotta; Ricardo J. Camacho; Suzie Coughlan; Algirdas Griskevicius; Zehava Grossman; Andrzej Horban; Leondios G. Kostrikis; Snjezana Lepej; Kirsi Liitsola; Marek Linka; Claus Nielsen; Dan Otelea; Roger Paredes; Mario Poljak; Elisabeth Puchhammer-Stockl; Jean-Claude Schmit; Anders Sonnerborg; Danica Stanekova; Maja Stanojevic; Charles A.B. Boucher; Lauren Kaplan; Anne-Mieke Vandamme; Dimitrios Paraskevis.
Global dispersal pattern of HIV-1 CRF01_AE: A genetic trace of human mobility related to heterosexual activities centralized in South-East Asia
Journal of Infectious Diseases, 2015, 211.11: 1735-1744.Volume 211 Issue 11 June 1, 2015doi: 10.1093/infdis/jiu666
Impact Factor: 5.778
Ani Kevorkyan, Pavel Teoharov, Tinne Lernout, Nedyalka Petrova, Ralitsa Raycheva, Ivailo Ivanov, Pierre van Damme, and Mira Kojouharova.
Prevalence of HBV and HCV among Outpatients in the Plovdiv Region of Bulgaria, 2010–2011
Journal of Medical Virology, Article first published online:27 AUG 2014 | DOI: 10.1002/jmv.24065
Impact Factor: 2.373
Frentz D, Van de Vijver DA, Abecasis AB, Albert J, Hamouda O, Jørgensen LB,Kücherer C, Struck D, Schmit JC, Vercauteren J, Åsjö B, Balotta C, Beshkov D,Camacho RJ, Clotet B, Coughlan S, Griskevicius A, Grossman Z, Horban A,Kolupajeva T, Korn K, Kostrikis LG, Liitsola K, Linka M, Nielsen C, Otelea D,Paraskevis D, Paredes R, Poljak M, Puchhammer-Stöckl E, Sönnerborg A, StanekovaD, Stanojevic M, Van Wijngaerden E, Wensing AM, Boucher CA; SPREAD Programme.
Increase in transmitted resistance to non-nucleoside reverse transcriptaseinhibitors among newly diagnosed HIV-1 infections in Europe.
BMC Infect Dis.2014Jul 21;14:407.
Impact Factor: 4.77
Frentz D, van de Vijver D, Abecasis A, Albert J, Hamouda O, Jørgensen L,Kücherer C, Struck D, Schmit JC, Vercauteren J, Asjö B, Balotta C, Bergin C, Beshkov D, Camacho R, Clotet B, Griskevicius A, Grossman Z, Horban A, KolupajevaT, Korn K, Kostrikis L, Linka KL, Nielsen C, Otelea D, Paraskevis D, Paredes R,Poljak M, Puchhammer-Stöckl E, Sönnerborg A, Stanekova D, Stanojevic M, VandammeAM, Boucher C, Wensing A; SPREAD Programme.
Patterns of transmitted HIV drug resistance in europe vary by risk group.
PLoS One. 2014 Apr 10;9(4):e94495
Impact Factor: 3.73
Frentz D, Wensing AM, Albert J, Paraskevis D, Abecasis AB, Hamouda O,Jørgensen LB, Kücherer C, Struck D, Schmit JC, Åsjö B, Balotta C, Beshkov D,Camacho RJ, Clotet B, Coughlan S, De Wit S, Griskevicius A, Grossman Z, Horban A,Kolupajeva T, Korn K, Kostrikis LG, Liitsola K, Linka M, Nielsen C, Otelea D, Paredes R, Poljak M, Puchhammer-Stöckl E, Sönnerborg A, Stanekova D, StanojevicM, Vandamme AM, Boucher CA, Van de Vijver DA; SPREAD Programme.
Limitedcross-border infections in patients newly diagnosed with HIV in Europe.
Retrovirology. 2013 Apr 3;10:36
Impact Factor: 4.77
Alexiev I, Beshkov D, Shankar A, Hanson DL, Paraskevis D, Georgieva V,Karamacheva L, Taskov H, Varleva T, Elenkov I, Stoicheva M, Nikolova D, SwitzerWM.
Detailed molecular epidemiologic characterization of HIV-1 infection inBulgaria reveals broad diversity and evolving phylodynamics.
PLoS One.2013;8(3):e59666
Impact Factor: 3.73
Abecasis AB, Wensing AM, Paraskevis D, Vercauteren J, Theys K, Van de VijverDA, Albert J, Asjö B, Balotta C, Beshkov D, Camacho RJ, Clotet B, De Gascun C, Griskevicius A, Grossman Z, Hamouda O, Horban A, Kolupajeva T, Korn K, Kostrikis LG, Kücherer C, Liitsola K, Linka M, Nielsen C, Otelea D, Paredes R, Poljak M, Puchhammer-Stöckl E, Schmit JC, Sönnerborg A, Stanekova D, Stanojevic M, StruckD, Boucher CA, Vandamme AM.
HIV-1 subtype distribution and its demographicdeterminants in newly diagnosed patients in Europe suggest highlycompartmentalized epidemics.
Retrovirology. 2013 Jan 14;10:7.
Impact Factor: 4.77
Stanojevic M, Alexiev I, Beshkov D, Gökengin D, Mezei M, Minarovits J, OteleaD, Paraschiv S, Poljak M, Zidovec-Lepej S, Paraskevis D.
HIV‑1 molecularepidemiology in the Balkans: a melting pot for high genetic diversity.
AIDS Rev.2012 Jan-Mar;14(1):28-36. Review.PubMed PMID: 22297502.
Impact Factor: 4.075
Ivanka Stankova,Kamelia Stanoeva,Anton Hinkov,Ivailo Alexiev,Petya Genova-Kalou,Radoslav Chayrov and Radka Argirova.
Amino acid and peptide esters of abacavir: synthesis and activity against human immunodeficiency virus type 1 in cell culture.
Medicinal Chemistry Research December 2012, Volume 21, Issue 12, pp 4053-4059
Impact Factor: 1.612
Santoro MM, Ciccozzi M, Alteri C, Montieri S, Alexiev I, Dimova I, Ceccherini-Silberstein F, Beshkov D, Rezza G, Perno CF.
Characterization ofdrug-resistance mutations in HIV type 1 isolates from drug-naive and ARV-treatedpatients in Bulgaria.
AIDS Res Hum Retroviruses. 2008 Sep;24(9):1133-8.
Impact Factor: 2.024
Salemi M, Goodenow MM, Montieri S, de Oliveira T, Santoro MM, Beshkov D,Alexiev I, Elenkov I, Elenkov I, Yakimova T, Varleva T, Rezza G, Ciccozzi M.
TheHIV type 1 epidemic in Bulgaria involves multiple subtypes and is sustained bycontinuous viral inflow from West and East European countries.
AIDS Res HumRetroviruses. 2008 Jun;24(6):771-9
Impact Factor: 2.024
Polianova M, Alexandrov M, Sovová V, Simeonov K, Roussev R, Beshkov D,Todorov TG.
A threshold level of gag expression is required for particleformation in rat cells transformed by avian retroviruses.
Folia Biol (Praha).1999;45(6):233-41
Impact Factor: 1.2
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