St. Laboratory 

Dr. Iva Ognyanova Filipova

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Tel. 359/ 2 944 69 99 / ext. 205 /

• Maria Borisova - lab. worker

Research conducted in the laboratory

Lab Activity

INSTRUCTIONS FOR RECEIVING, PACKAGING AND TRANSPORTING MATERIALS</a >

SPI laboratory activity plan in 2024 .

Inguinal lymphogranulomatosis

Antibiotic Resistance Guided Therapy

An active research activity is carried out in the NRL SPI, and the most significant scientific topics in recent years are:

1. "Molecular genetic approach to support the surveillance of antibiotic resistance of gonorrhea and genital mycoplasma infection", funded by FNI, contract No. ДН13/5 of 2017
   
   
2. "Study of the public health benefits of extragenital chlamydia and gonorrhea testing", funded by the National Institute of Scientific Research, contract No. KP-06-M33/1 of 2019

The results of the scientific activity of the laboratory during the last five years are presented in the following publications in international and national refereed journals:

1. Philipova I, Levterova V, Simeonovski I, Kantardjiev T. Antimicrobial Resistance and Whole Genome Sequencing Analysis of Neisseria gonorrhoeae Isolates in Bulgaria, 2019. Comptes rendus l’Académie Bulg des Sci Sci mathématiques Nat. 2022;75(11):1579–87. IF 0.326

2. Philipova I, Levterova V, Simeonovski I, Kantardjiev T. Azithromycin treatment failure and macrolide resistance in Mycoplasma genitalium infections in Sofia, Bulgaria. Folia medica (Plovdiv). 2022;64(3):422–9. Q4

3. Philipova I, Levterova V, Simeonovski I, Kantardjiev T. High rate of fluoroquinolone resistant Neisseria gonorrhoeae detected by molecular surveillance of antimicrobial resistance determinants in Bulgaria. Biotechnol Biotechnol Equip. 2022;36(1):942–8. IF1.762

4. Philipova I, Birindjieva E, Milanov A, Stoitsova S. Prevalence of pharyngeal and rectal Chlamydia trachomatis and Neisseria gonorrhoeae infections among MSM in Sofia, Bulgaria. Probl Infect Parasit Dis. 2022; Q4

5. Philipova I, Stoitsova S, Birindjieva E, Milanov A, Levterova V. First confirmed Lymphogranuloma venereum (LGV) cases among MSM in Bulgaria, 2020–2021. World J Adv Res Rev. 2022;14(3):670–673.

6. Pakov I, Birindzhieva E, Philipova I, Terzieva K, Gancheva G. PRE-EXPOSURE PROPHYLAXIS (PREP) OF HIV INFECTION – A CRUCIAL TOOL FOR REDUCING THE BURDEN UPON THE PUBLIC HEALTH. J IMAB - Annu Proceeding (Scientific Pap. 2022;28(4):4688–90. Q3

7. Kohlenberg A, Monnet DL, Plachouras D. Increasing number of cases and outbreaks caused by Candida auris in the EU / EEA, 2020 to 2021. Eurosurveillance. 2022;27(46):1–6. IF21.286

8. Brito AF, Semenova E, Dudas G, Hassler GW, Kalinich CC, Kraemer MUG, et al. Global disparities in SARS-CoV-2 genomic surveillance. Nat Commun. 2022;13(1):7003. IF 17.694

9. Alexiev I, Giovanetti M, Cella E, Ivanov I, Stoikov I, Donchev D, et al. Initial introduction and spread of the SARS-CoV-2 AY. 4.2. 1 Delta variant in Bulgaria, a genomic insight. J Med Virol. 2022;94(12):6060–4. IF 20.693

10. Levterova VS, Simeonovski IM, Brankova NB, Ivanova MV, Philipova IO, Malcheva MR. Carriage and distribution of serotypes Streptococcus pneumoniae in healthy vaccinated children for the year 2021 in Bulgaria. World J Adv Res Rev. 2022;14(3):511–6.

11. Alexiev I, Ivanov I, Philipova I, Korsun N, Stoikov I, Dimitrova R, Grigorova L, Gancheva A, Trifonova I, Dobrinov V, Grigorova I. Postvaccination SARS‐CoV‐2 Alpha (B. 1.1. 7) lineage infection among healthcare workers on the background of IgG antibodies. Journal of Medical Virology. 2022 Mar;94(3):836. IF 20.693

12. Philipova I, Levterova V, Simeonovski I, Ivanova Z, Boyanova L, Kantardjiev T. Prevalence of Neisseria gonorrhoeae and Mycoplasma genitalium in Bulgarian population of reproductive age from Sofia Municipality, 2018-2019. PROBLEMS of Infectious and Parasitic Diseases. 2021 Aug 27;49(2):20-6. Q4

13. Malcheva M, Philipova I, Simeonovski I, Levterova V, Brankova N, Kantardjiev T. ANTIMICROBIAL SUSCEPTIBILITY OF S. PNEUMONIAE STRAINS ISOLATED FROM CHILDREN WITH NASOPHARYNGEAL CARRIAGE. PROBLEMS of Infectious and Parasitic Diseases. 2020 May 12;48(1):15-20. Q4

14. Plachouras D, Lötsch F, Kohlenberg A, Monnet DL, Candida auris Survey Collaborative Group. Candida auris: epidemiological situation, laboratory capacity and preparedness in the European Union and European Economic Area*, January 2018 to May 2019. Eurosurveillance. 2020 Mar 26;25(12):2000240. IF 6.307

15. Kohlenberg A, Struelens MJ, Monnet DL, Plachouras D, Candida Auris Survey Collaborative Group. Candida auris: epidemiological situation, laboratory capacity and preparedness in European Union and European Economic Area countries, 2013 to 2017. Eurosurveillance. 2018 Mar 29;23(13):18-00136. IF 7.421